What Is The Difference Between Interferon And Peginterferon?

What does a interferon do?

Interferons are proteins that are part of your natural defenses.

They tell your immune system that germs or cancer cells are in your body.

And they trigger killer immune cells to fight those invaders.

Interferons got their name because they “interfere” with viruses and keep them from multiplying..

How much does interferon cost?

The high cost of interferon and ribavirin treatment—approximately $30,000 for 48 weeks—would need to be added to either treatment. (Ribavirin is a pill available under various brand names. Pegylated interferon is sold under several brand names and is injected, typically by the patient.)

What is the difference between interferon alpha 2a and 2b?

The main difference between these two pegylated interferons is in the dosing. Alfa-2a is used as a fixed weekly dose. Alfa-2b is used as a weekly dose based on the weight of the patient. There are other differences between the two drugs, but they are mostly technical and are used by the prescribing physician.

Does interferon kill viruses?

Interferon is secreted by cells in response to stimulation by a virus or other foreign substance, but it does not directly inhibit the virus’s multiplication. Rather, it stimulates the infected cells and those nearby to produce proteins that prevent the virus from replicating within them.

Is interferon an antiviral?

The interferons (IFNs) are glycoproteins with strong antiviral activities that represent one of the first lines of host defense against invading pathogens. These proteins are classified into three groups, Type I, II and III IFNs, based on the structure of their receptors on the cell surface.

Does interferon cause depression?

Interferon alpha (IFN-α)-induced depression is a common and severe psychiatric disorder in IFN-α therapy for hepatitis C virus (HCV)-infected patients.

Is interferon a chemo drug?

Interferon-alfa2b is different than a chemotherapy drug; it is actually a natural part of your body’s immune system. It is known as a cytokine, which are chemicals normally secreted by cells called leukocytes in response to a virus, bacteria, or other foreign intruders.

How does pegylated interferon work?

How PEG Interferon Works: PEG Interferon alfa-2b is interferon alfa-2b with a substance called polyethylene glycol (PEG) attached to it. The attachment process is called pegylation, and is used to allow active substances (the interferon alfa-2b) to stay in the body longer before they are broken down and eliminated.

How long does interferon treatment last?

Why interferons cause long-term side effects Interferon treatment for hepatitis C would typically last 24–48 weeks (6–12 months). Interferons caused many long-term side effects partly because of this long treatment time. Using the drug for this length of time gave side effects a chance to develop and get worse.